PhD scholarship in Genome Engineering

Friday 23 Oct 20

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Apply no later than 6 November 2020
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We are seeking an outstanding candidate for a 3-year fully funded Ph.D-studentship to join a highly international research center - The Novo Nordisk Foundation for Biosustainability, Technical University of Denmark, and become part of the Microbial Evolution and Synthetic Biology Group headed by Morten Nørholm.

The PhD project will be part of a larger team effort to develop true genome engineering, e.g.

  • Develop, implement, and apply genome reduction techniques to generate minimal genomes in the model bacterium Escherichia coli
  • Implement large scale genome editing for inserting 100Kb segments into the E. coli genome
  • Evaluate the orthogonality of independently-modulated gene sets (iModulons)
  • Re-engineer and optimize genomes using laboratory evolution

Responsibilities and tasks
The successful candidate will be working on genome engineering and experimental evolution approaches for studying microbial cell factories. The position is funded by the Novo Nordisk Foundation and the successful candidate will join a team of scientists working with synthetic biology, protein production and molecular evolution.

Qualifications
Candidates should have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

We are looking for a highly motivated individual with a MSc degree in synthetic/molecular/microbiology or related discipline. Candidates with experience in state-of-the-art microbial genetic engineering and/or experimental evolution will be preferred.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Morten Nørholm, morno@biosustain.dtu.dk

Application
Please submit your online application no later than 6 November 2020 (Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)

Candidates may apply prior to ob­tai­ning their master's degree but cannot begin before having received it.

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods.

Learn more at biosustain.dtu.dk

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.

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